Pseudomonas aeruginosa PAO1, PA0691 (phdA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0691
Name
phdA
Replicon chromosome
Genomic location 762891 - 763493 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249382.1
GI 15595888
Affymetrix PA0691_at
Entrez 880799
GenBank AAG04080.1
INSDC AAG04080.1
NCBI Locus Tag PA0691
protein_id(GenBank) gb|AAG04080.1|AE004505_1|gnl|PseudoCAP|PA0691
TIGR NTL03PA00692
UniParc UPI00000C5102
UniProtKB Acc Q9I5N5
UniProtKB ID Q9I5N5_PSEAE
UniRef100 UniRef100_W0Z0M8
UniRef50 UniRef50_Q1I9R1
UniRef90 UniRef90_A6VAS6

Product

Feature Type CDS
Coding Frame 1
Product Name
prevent-host-death protein A
Product Name Confidence: Class 1
Synonyms PhdA
Evidence for Translation
Charge (pH 7) 0.19
Kyte-Doolittle Hydrophobicity Value 0.018
Molecular Weight (kDa) 22.8
Isoelectric Point (pI) 7.09

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 42 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000670 (556 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0691
Search term: phdA

Human Homologs

References

The novel Pseudomonas aeruginosa two-component regulator BfmR controls bacteriophage-mediated lysis and DNA release during biofilm development through PhdA.
Petrova OE, Schurr JR, Schurr MJ, Sauer K
Mol Microbiol 2011 Aug;81(3):767-83
PubMed ID: 21696457