Pseudomonas aeruginosa PAO1, PA0846

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0846
Name
Synonym: cysZ
Replicon chromosome
Genomic location 924182 - 924922 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249537.1
GI 15596043
Affymetrix PA0846_at
DNASU PaCD00006388
Entrez 880298
GenBank AAG04235.1
INSDC AAG04235.1
NCBI Locus Tag PA0846
protein_id(GenBank) gb|AAG04235.1|AE004519_6|gnl|PseudoCAP|PA0846
TIGR NTL03PA00847
UniParc UPI0000128D55
UniProtKB Acc Q9I595
UniProtKB ID CYSZ_PSEAE
UniRef100 UniRef100_Q9I595
UniRef50 UniRef50_Q9I595
UniRef90 UniRef90_Q9I595

Product

Feature Type CDS
Coding Frame 1
Product Name
probable sulfate uptake protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 3.44
Kyte-Doolittle Hydrophobicity Value 0.818
Molecular Weight (kDa) 28.0
Isoelectric Point (pI) 9.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 112 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000813 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0846

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
DNA sequences of the cysK regions of Salmonella typhimurium and Escherichia coli and linkage of the cysK regions to ptsH.
Byrne CR, Monroe RS, Ward KA, Kredich NM
J Bacteriol 1988 Jul;170(7):3150-7
PubMed ID: 3290198
Phylogeny of metabolic pathways: O-acetylserine sulphydrylase A is homologous to the tryptophan synthase beta subunit.
Levy S, Danchin A
Mol Microbiol 1988 Nov;2(6):777-83
PubMed ID: 3062311