Pseudomonas aeruginosa PAO1, PA0884

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0884
Name
Synonym: dctP
Replicon chromosome
Genomic location 966526 - 967521 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249575.1
GI 15596081
Affymetrix PA0884_at
DNASU PaCD00006406
Entrez 878364
GenBank AAG04273.1
INSDC AAG04273.1
NCBI Locus Tag PA0884
protein_id(GenBank) gb|AAG04273.1|AE004523_1|gnl|PseudoCAP|PA0884
TIGR NTL03PA00885
UniParc UPI00000C51A6
UniProtKB Acc Q9I561
UniProtKB ID Q9I561_PSEAE
UniRef100 UniRef100_W0YLD5
UniRef50 UniRef50_Q8ECK4
UniRef90 UniRef90_W0YLD5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable C4-dicarboxylate-binding periplasmic protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) 2.91
Kyte-Doolittle Hydrophobicity Value -0.328
Molecular Weight (kDa) 37.2
Isoelectric Point (pI) 8.64

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Periplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 251 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000851 (1023 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0884

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Purification, characterization and nucleotide sequence of the periplasmic C4-dicarboxylate-binding protein (DctP) from Rhodobacter capsulatus.
Shaw JG, Hamblin MJ, Kelly DJ
Mol Microbiol 1991 Dec;5(12):3055-62
PubMed ID: 1809844
TRAP transporters: a new family of periplasmic solute transport systems encoded by the dctPQM genes of Rhodobacter capsulatus and by homologs in diverse gram-negative bacteria.
Forward JA, Behrendt MC, Wyborn NR, Cross R, Kelly DJ
J Bacteriol 1997 Sep;179(17):5482-93
PubMed ID: 9287004