Pseudomonas aeruginosa PAO1, PA0961

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0961
Name
Replicon chromosome
Genomic location 1046720 - 1046911 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249652
GI 15596158
Affymetrix PA0961_at
DNASU PaCD00006442
Entrez 882013
GenBank AAG04350.1
NCBI Locus Tag PA0961
protein_id(GenBank) gb|AAG04350.1|AE004530_3|gnl|PseudoCAP|PA0961
TIGR NTL03PA00962
UniProtKB Acc Q9I4Z8
UniProtKB ID Q9I4Z8_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
probable cold-shock protein
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.47
Kyte-Doolittle Hydrophobicity Value -0.413
Molecular Weight (kDa) 7.2
Isoelectric Point (pI) 10.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 2
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 479 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000926 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0961

Human Homologs

References

CspA, the major cold shock protein of Escherichia coli, negatively regulates its own gene expression.
Bae W, Jones PG, Inouye M
J Bacteriol 1997 Nov;179(22):7081-8
PubMed ID: 9371456
The cold shock response of the psychrotrophic bacterium Pseudomonas fragi involves four low-molecular-mass nucleic acid-binding proteins.
Michel V, Lehoux I, Depret G, Anglade P, Labadie J, Hebraud M
J Bacteriol 1997 Dec;179(23):7331-42
PubMed ID: 9393697
The CspA family in Escherichia coli: multiple gene duplication for stress adaptation.
Yamanaka K, Fang L, Inouye M
Mol Microbiol 1998 Jan;27(2):247-55
PubMed ID: 9484881