Pseudomonas aeruginosa PAO1, PA1001 (phnA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1001
Name
phnA
Replicon chromosome
Genomic location 1083972 - 1085564 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq NP_249692.1
GI 15596198
Affymetrix PA1001_phnA_at
Entrez 878421
GenBank AAG04390.1
INSDC -
NCBI Locus Tag PA1001
protein_id(GenBank) gb|AAG04390.1|AE004533_1|gnl|PseudoCAP|PA1001
TIGR NTL03PA01002
UniParc UPI000013198E
UniProtKB Acc P09785
UniProtKB ID PHNA_PSEAE
UniRef100 UniRef100_P09785
UniRef50 UniRef50_P09785
UniRef90 UniRef90_P09785

Product

Feature Type CDS
Coding Frame 1
Product Name
anthranilate synthase component I
Product Name Confidence: Class 1
Synonyms phenazine biosynthesis protein PhnA
Evidence for Translation
Charge (pH 7) -10.48
Kyte-Doolittle Hydrophobicity Value -0.235
Molecular Weight (kDa) 58.7
Isoelectric Point (pI) 5.87

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 598 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000964 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1001
Search term: phnA

Human Homologs

References

Structure and regulation of the anthranilate synthase genes in Pseudomonas aeruginosa: I. Sequence of trpG encoding the glutamine amidotransferase subunit.
Crawford IP, Eberly L
Mol Biol Evol 1986 Sep;3(5):436-48
PubMed ID: 3127654
Identification and characterization of genes for a second anthranilate synthase in Pseudomonas aeruginosa: interchangeability of the two anthranilate synthases and evolutionary implications.
Essar DW, Eberly L, Hadero A, Crawford IP
J Bacteriol 1990 Feb;172(2):884-900
PubMed ID: 2153661