Pseudomonas aeruginosa PAO1, PA1294 (rnd)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1294
Name
rnd
Replicon chromosome
Genomic location 1405338 - 1406462 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249985.1
GI 15596491
Affymetrix PA1294_rnd_at
Entrez 881579
GenBank AAG04683.1
INSDC AAG04683.1
NCBI Locus Tag PA1294
protein_id(GenBank) gb|AAG04683.1|AE004559_2|gnl|PseudoCAP|PA1294
TIGR NTL03PA01295
UniParc UPI00000C52F5
UniProtKB Acc Q9I450
UniProtKB ID Q9I450_PSEAE
UniRef100 UniRef100_W0YLI0
UniRef50 UniRef50_A6V8R6
UniRef90 UniRef90_A6V8R6

Product

Feature Type CDS
Coding Frame 1
Product Name
ribonuclease D
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -12.89
Kyte-Doolittle Hydrophobicity Value -0.399
Molecular Weight (kDa) 43.1
Isoelectric Point (pI) 4.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 285 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001238 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1294
Search term: rnd
Search term: ribonuclease D

Human Homologs

References

Escherichia coli RNase D: sequencing of the rnd structural gene and purification of the overexpressed protein.
Zhang JR, Deutscher MP
Nucleic Acids Res 1988 Jul 25;16(14A):6265-78
PubMed ID: 3041371