Pseudomonas aeruginosa UCBPP-PA14, PA14_01110 (vgrG1a)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag
PA14_01110
Name
vgrG1a
Replicon chromosome
Genomic location 108629 - 110560 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 48 transposon mutants in orthologs

Cross-References

RefSeq YP_788248.1
GI 116053811
Entrez 4383509
NCBI Locus Tag PA14_01110

Product

Feature Type CDS
Coding Frame 1
Product Name
VgrG1a
Product Name Confidence: Class 1
CommentHcp Secretion Island-I-encoded type VI secretion system (H1-T6SS)
Evidence for Translation
Charge (pH 7) -7.09
Kyte-Doolittle Hydrophobicity Value -0.538
Molecular Weight (kDa) 72041.1
Isoelectric Point (pI) 6.28

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4UHV STRUCTURAL PROTEIN 03/25/15 The structure of VgrG1, the needle tip of the bacterial Type VI Secretion System PSEUDOMONAS AERUGINOSA 2.0 X-RAY DIFFRACTION 99.7
4MTK TOXIN 09/19/13 Crystal structure of PA0091 VgrG1, the central spike of the Type VI Secretion System PSEUDOMONAS AERUGINOSA 3.322 X-RAY DIFFRACTION 99.7

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 156 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3427 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_01110
Search term: vgrG1a
Search term: VgrG1a

References

Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
Hachani A, Lossi NS, Hamilton A, Jones C, Bleves S, Albesa-Jové D, Filloux A
J. Biol. Chem. 2011 Apr;286(14):12317-27
PubMed ID: 21325275
PubMed ID: 28673999