Pseudomonas aeruginosa UCBPP-PA14, PA14_03200 (tle3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_03200
Name
tle3
Replicon chromosome
Genomic location 282565 - 284715 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_788413.1
GI 116053973
Entrez 4383671
INSDC ABJ15209.1
NCBI Locus Tag PA14_03200
UniParc UPI0000E448A1
UniProtKB Acc Q02UH3
UniProtKB ID Q02UH3_PSEAB
UniRef100 UniRef100_Q02UH3
UniRef50 UniRef50_Q9I6M9
UniRef90 UniRef90_Q9I6M9

Product

Feature Type CDS
Coding Frame 1
Product Name
Type VI effector Tle3
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Charge (pH 7) 0.91
Kyte-Doolittle Hydrophobicity Value -0.397
Molecular Weight (kDa) 78.3
Isoelectric Point (pI) 7.12

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 17 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000258 (272 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_03200
Search term: tle3

Human Homologs

References

RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A
Proc Natl Acad Sci U S A 2017 Jul 18;114(29):7707-7712
PubMed ID: 28673999