Pseudomonas aeruginosa UCBPP-PA14, PA14_04760 (coaD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_04760
Name
coaD
Replicon chromosome
Genomic location 421371 - 421850 (- strand)

Cross-References

RefSeq YP_788535.1
GI 116054092
EC Number 2.7.7.3
Entrez 4384288
INSDC ABJ15328.1
NCBI Locus Tag PA14_04760
UniParc UPI0000127CC2
UniProtKB Acc Q02U51
UniProtKB ID COAD_PSEAB
UniRef100 UniRef100_B7V2S6
UniRef50 UniRef50_Q5ZY26
UniRef90 UniRef90_B7V2S6

Product

Feature Type CDS
Coding Frame 1
Product Name
phosphopantetheine adenylyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) 2.19
Kyte-Doolittle Hydrophobicity Value -0.007
Molecular Weight (kDa) 17.8
Isoelectric Point (pI) 8.95

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
5X6F TRANSFERASE 02/21/17 Crystal structure of Phosphopantetheine adenylyltransferase from Pseudomonas aeruginosa Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) 2.593 X-RAY DIFFRACTION 100.0
4RUK TRANSFERASE 11/20/14 crystal structure of Phosphoapantetheine adenylyltransferase PPAT/CoaD with CoA and pyrophosphate from Pseudomonas aeruginosa Pseudomonas aeruginosa 2192 2.2 X-RAY DIFFRACTION 100.0
3X1K TRANSFERASE 11/20/14 crystal structure of Phosphoapantetheine adenylyltransferase PPAT/CoaD with AMP-PNP from Pseudomonas aerugonosa Pseudomonas aeruginosa 2192 2.547 X-RAY DIFFRACTION 100.0
5TS2 TRANSFERASE 10/27/16 Crystal structure of a phosphopantetheine adenylyltransferase (CoaD, PPAT) from Pseudomonas aeruginosa bound to dephospho coenzyme A Pseudomonas aeruginosa (strain LESB58) 2.3 X-RAY DIFFRACTION 100.0
3X1M TRANSFERASE 11/24/14 Crystal structure of Phosphopantetheine adenylyltransferase/PPAT from Pseudomonas aeruginosa with CoA Pseudomonas aeruginosa 2192 2.5 X-RAY DIFFRACTION 100.0
3X1J TRANSFERASE 11/19/14 Crystal Structure of Phosphopantetheine adenylyltransferase (PPAT/CoaD) with AcCoA from Pseudomonas aeruginosa Pseudomonas aeruginosa 2192 2.334 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 578 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000354 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_04760
Search term: coaD

Human Homologs

References

No references are associated with this feature.