Strain |
Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest |
Locus Tag |
PA14_07500
|
Name |
rmcA
|
Replicon | chromosome |
Genomic location | 643347 - 647084 (- strand) |
Transposon Mutants | 2 transposon mutants in UCBPP-PA14 |
Transposon Mutants in orthologs | 9 transposon mutants in orthologs |
RefSeq | YP_788748.1 |
GI | 116054303 |
Entrez | 4384222 |
INSDC | ABJ15539.1 |
NCBI Locus Tag | PA14_07500 |
UniParc | UPI000045D43F |
UniProtKB Acc | Q02TI8 |
UniProtKB ID | Q02TI8_PSEAB |
UniRef100 | UniRef100_Q02TI8 |
UniRef50 | UniRef50_Q4K4W0 |
UniRef90 | UniRef90_Q9I5W1 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
redox regulator of c_di_GMP, RmcA
|
Synonyms | |
Evidence for Translation | |
Charge (pH 7) | -29.53 |
Kyte-Doolittle Hydrophobicity Value | -0.176 |
Molecular Weight (kDa) | 139.7 |
Isoelectric Point (pI) | 5.51 |
Individual Mappings | |
Additional evidence for subcellular localization |
Accession | Header | Accession Date | Compound | Source | Resolution | Method | Percent Identity |
5M3C | HYDROLASE | 10/14/16 | Structure of the hybrid domain (GGDEF-EAL) of PA0575 from Pseudomonas aeruginosa PAO1 at 2.8 Ang. with GTP and Ca2+ bound to the active site of the GGDEF domain | Pseudomonas aeruginosa | 2.8 | X-RAY DIFFRACTION | 99.5 |
7EJG | PEPTIDE BINDING PROTEIN | 04/02/21 | Crystal structure of PBP domain of RMCA | Pseudomonas aeruginosa | 1.68 | X-RAY DIFFRACTION | 98.7 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 563 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000558 (491 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA14_07500
Search term: rmcA
Search term: redox regulator of c_di_GMP, RmcA
|
Insights into the GTP-dependent allosteric control of c-di-GMP hydrolysis from the crystal structure of PA0575 protein from Pseudomonas aeruginosa.
Mantoni F, Paiardini A, Brunotti P, D'Angelo C, Cervoni L, Paone A, Cappellacci L, Petrelli R, Ricciutelli M, Leoni L, Rampioni G, Arcovito A, Rinaldo S, Cutruzzolà F, Giardina G
FEBS J 2018 Oct;285(20):3815-3834
PubMed ID: 30106221
|
Electron-shuttling antibiotics structure bacterial communities by modulating cellular levels of c-di-GMP.
Okegbe C, Fields BL, Cole SJ, Beierschmitt C, Morgan CJ, Price-Whelan A, Stewart RC, Lee VT, Dietrich LEP
Proc Natl Acad Sci U S A 2017 Jun 27;114(26):E5236-E5245
PubMed ID: 28607054
|