Pseudomonas aeruginosa UCBPP-PA14, PA14_16280

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_16280
Name
Replicon chromosome
Genomic location 1390844 - 1391485 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_789443.1
GI 116051718
Entrez 4380218
INSDC ABJ12954.1
NCBI Locus Tag PA14_16280
UniParc UPI0000396168
UniProtKB Acc Q02RJ3
UniProtKB ID Q02RJ3_PSEAB
UniRef100 UniRef100_S0HTU6
UniRef50 UniRef50_Q9HXS0
UniRef90 UniRef90_Q9HXS0

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator
Synonyms
Evidence for Translation
Charge (pH 7) -3.89
Kyte-Doolittle Hydrophobicity Value -0.086
Molecular Weight (kDa) 23.7
Isoelectric Point (pI) 5.66

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AMR gene predictions from CARD database

Identified using the Resistance Gene Identifier (RGI)

Model Name Definition Accession Model Type (?) SNP Cutoff Bit Score Percent Identity CARD Version
nalC NalC is a repressor of PA3720-PA3719, which are positive regulators of MexAB-OprM. Thus, nalC mutants confer multidrug resistance. [PMID:27060003, PMID:27412168, PMID:15387820] ARO:3000818 protein overexpression model S209R, G71E Strict 412.1 98.59 3.2.5

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 310 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001962 (826 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_16280

Human Homologs

References

No references are associated with this feature.