Pseudomonas aeruginosa UCBPP-PA14, PA14_16550

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_16550
Name
Replicon chromosome
Genomic location 1417317 - 1418030 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_789465.1
GI 116051696
Entrez 4384648
INSDC ABJ12932.1
NCBI Locus Tag PA14_16550
UniParc UPI00000C5AC7
UniProtKB Acc Q02RH1
UniProtKB ID Q02RH1_PSEAB
UniRef100 UniRef100_W0YY78
UniRef50 UniRef50_W6QRX7
UniRef90 UniRef90_A6V188

Product

Feature Type CDS
Coding Frame 1
Product Name
TetR family transcriptional regulator
Synonyms
Evidence for Translation
Charge (pH 7) -4.03
Kyte-Doolittle Hydrophobicity Value -0.078
Molecular Weight (kDa) 26.3
Isoelectric Point (pI) 5.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3KKD transcription regulator 11/05/09 Structure of a putative tetr transcriptional regulator (pa3699) from pseudomonas aeruginosa pa01 Pseudomonas aeruginosa PAO1 2.1 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 60 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001978 (500 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_16550

Human Homologs

References

Colony-morphology screening uncovers a role for the Pseudomonas aeruginosa nitrogen-related phosphotransferase system in biofilm formation.
Cabeen MT, Leiman SA, Losick R
Mol Microbiol 2016 Feb;99(3):557-70
PubMed ID: 26483285