Pseudomonas aeruginosa UCBPP-PA14, PA14_17210 (lpxA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_17210
Name
lpxA
Replicon chromosome
Genomic location 1475049 - 1475825 (+ strand)

Cross-References

RefSeq YP_789520.1
GI 116051641
EC Number 2.3.1.129
Entrez 4383257
INSDC ABJ12877.1
NCBI Locus Tag PA14_17210
UniParc UPI000012E8B4
UniProtKB Acc Q02RB6
UniProtKB ID LPXA_PSEAB
UniRef100 UniRef100_A6V1E4
UniRef50 UniRef50_P32201
UniRef90 UniRef90_A4XWS9

Product

Feature Type CDS
Coding Frame 1
Product Name
UDP-N-acetylglucosamine acyltransferase
Synonyms
Evidence for Translation
Charge (pH 7) 0.30
Kyte-Doolittle Hydrophobicity Value -0.118
Molecular Weight (kDa) 28.0
Isoelectric Point (pI) 7.05

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
7OKB TRANSFERASE 05/17/21 Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 45 Pseudomonas aeruginosa 3.58 X-RAY DIFFRACTION 100.0
7OKA TRANSFERASE 05/17/21 Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 14 Pseudomonas aeruginosa (strain PA7) 2.74 X-RAY DIFFRACTION 100.0
7OK2 TRANSFERASE 05/17/21 Crystal structure of Pseudomonas aeruginosa LpxA in complex with compound 3 Pseudomonas aeruginosa (strain PA7) 2.89 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 433 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002030 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_17210
Search term: lpxA

Human Homologs

References

No references are associated with this feature.