Pseudomonas aeruginosa UCBPP-PA14, PA14_17290 (pyrG)

Gene Feature Overview

Strain	Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006) GCF_000014625.1|latest
Locus Tag	PA14_17290
Name	pyrG
Replicon	chromosome
Genomic location	1485522 - 1487150 (+ strand)

Cross-References

RefSeq	YP_789527.1
GI	116051634
EC Number	6.3.4.2
Entrez	4383250
INSDC	ABJ12870.1
NCBI Locus Tag	PA14_17290
UniParc	UPI0000132D75
UniProtKB Acc	Q02RA9
UniProtKB ID	PYRG_PSEAB
UniRef100	UniRef100_A6V1F1
UniRef50	UniRef50_P28595
UniRef90	UniRef90_A6V1F1

Product

Feature Type	CDS
Coding Frame	1
Product Name	CTP synthetase
Synonyms
Evidence for Translation
Charge (pH 7)	-13.54
Kyte-Doolittle Hydrophobicity Value	-0.152
Molecular Weight (kDa)	59.6
Isoelectric Point (pI)	5.38

Subcellular localization

Individual Mappings	Localization Confidence PMID Cytoplasmic Class 3 20472543
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results

Common Found in both pathogen and nonpathogenic strains Hits to this gene were found in 655 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database	View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group	POG002037 (537 members)
Putative Inparalogs	None Found

Interactions

STRING database

Search for predicted protein-protein interactions using: Search term: PA14_17290 Search term: pyrG Search term: CTP synthetase

Human Homologs

Ensembl 110, assembly GRCh38.p14	ENSP00000496792 CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] E-value: 1.7e-138 Percent Identity: 44.8
Ensembl 110, assembly GRCh38.p14	ENSP00000497744 CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] E-value: 1.7e-138 Percent Identity: 44.8
Ensembl 110, assembly GRCh38.p14	ENSP00000497901 CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] E-value: 1.7e-138 Percent Identity: 44.8
Ensembl 110, assembly GRCh38.p14	ENSP00000361699 CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] E-value: 1.7e-138 Percent Identity: 44.8
Ensembl 110, assembly GRCh38.p14	ENSP00000497602 CTP synthase 1 [Source:HGNC Symbol;Acc:HGNC:2519] E-value: 1.7e-138 Percent Identity: 44.8

References