Pseudomonas aeruginosa UCBPP-PA14, PA14_46070 (gbuA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_46070
Name
gbuA
Replicon chromosome
Genomic location 4096997 - 4097956 (+ strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq YP_791830.1
GI 116049367
Entrez 4382313
INSDC ABJ10603.1
NCBI Locus Tag PA14_46070
UniParc UPI000045D148
UniProtKB Acc Q02JQ6
UniProtKB ID Q02JQ6_PSEAB
UniRef100 UniRef100_Q02JQ6
UniRef50 UniRef50_Q9I3S3
UniRef90 UniRef90_Q9I3S3

Product

Feature Type CDS
Coding Frame 1
Product Name
guanidinobutyrase
Synonyms
Evidence for Translation
Charge (pH 7) -10.74
Kyte-Doolittle Hydrophobicity Value -0.046
Molecular Weight (kDa) 34.7
Isoelectric Point (pI) 5.07

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
3NIO HYDROLASE 06/16/10 Crystal structure of Pseudomonas aeruginosa guanidinobutyrase Pseudomonas aeruginosa 2 X-RAY DIFFRACTION 99.4

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 434 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001341 (475 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_46070
Search term: gbuA
Search term: guanidinobutyrase

Human Homologs

Ensembl 110, assembly GRCh38.p14
agmatinase [Source:HGNC Symbol;Acc:HGNC:18407]
E-value: 1.6e-112
Percent Identity: 61.3

References

No references are associated with this feature.