Pseudomonas aeruginosa UCBPP-PA14, PA14_51820 (aspS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_51820
Name
aspS
Replicon chromosome
Genomic location 4601301 - 4603076 (- strand)

Cross-References

RefSeq YP_792311.1
GI 116048888
EC Number 6.1.1.12
Entrez 4384451
INSDC ABJ10124.1
NCBI Locus Tag PA14_51820
UniParc UPI00001363AB
UniProtKB Acc Q02IC5
UniProtKB ID SYDND_PSEAB
UniRef100 UniRef100_B7UXW9
UniRef50 UniRef50_Q83BE5
UniRef90 UniRef90_C1DRG2

Product

Feature Type CDS
Coding Frame 1
Product Name
aspartyl-tRNA synthetase
Synonyms
Evidence for Translation
Charge (pH 7) -13.46
Kyte-Doolittle Hydrophobicity Value -0.297
Molecular Weight (kDa) 66.2
Isoelectric Point (pI) 5.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
4WJ3 LIGASE/RNA 09/29/14 Crystal structure of the asparagine transamidosome from Pseudomonas aeruginosa Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 3.705 X-RAY DIFFRACTION 100.0
4WJ4 LIGASE/RNA 09/29/14 Crystal structure of non-discriminating aspartyl-tRNA synthetase from Pseudomonas aeruginosa complexed with tRNA(Asn) and aspartic acid Pseudomonas aeruginosa PAO1; SYNTHETIC CONSTRUCT 3.294 X-RAY DIFFRACTION 100.0

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 669 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000928 (537 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_51820
Search term: aspS

Human Homologs

Ensembl 110, assembly GRCh38.p14
aspartyl-tRNA synthetase 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:25538]
E-value: 2.8e-118
Percent Identity: 39.9

References

No references are associated with this feature.