Pseudomonas aeruginosa UCBPP-PA14, PA14_53340

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_53340
Name
Replicon chromosome
Genomic location 4727802 - 4729814 (+ strand)
Transposon Mutants 2 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 3 transposon mutants in orthologs

Cross-References

RefSeq YP_792432.1
GI 116048768
Entrez 4385303
INSDC ABJ10004.1
NCBI Locus Tag PA14_53340
UniParc UPI000045D055
UniProtKB Acc Q02I04
UniProtKB ID Q02I04_PSEAB
UniRef100 UniRef100_Q02I04
UniRef50 UniRef50_Q9I596
UniRef90 UniRef90_Q9I596

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Synonyms
Evidence for Translation
Charge (pH 7) -4.77
Kyte-Doolittle Hydrophobicity Value -0.247
Molecular Weight (kDa) 73.3
Isoelectric Point (pI) 6.40

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
2ZWS HYDROLASE 12/17/08 Crystal Structure Analysis of neutral ceramidase from Pseudomonas aeruginosa Pseudomonas aeruginosa 1.4 X-RAY DIFFRACTION 99.2
2ZXC HYDROLASE 12/22/08 Ceramidase complexed with C2 Pseudomonas aeruginosa 2.2 X-RAY DIFFRACTION 99.2

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 40 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000812 (298 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_53340

Human Homologs

Ensembl 110, assembly GRCh38.p14
N-acylsphingosine amidohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:18860]
E-value: 5.4e-118
Percent Identity: 36.1
Ensembl 110, assembly GRCh38.p14
N-acylsphingosine amidohydrolase 2 [Source:HGNC Symbol;Acc:HGNC:18860]
E-value: 5.4e-118
Percent Identity: 36.1

References

No references are associated with this feature.