Pseudomonas aeruginosa PAO1, PA2245 (pslO)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA2245
Name
pslO
Replicon chromosome
Genomic location 2472104 - 2472409 (+ strand)
Transposon Mutants in orthologs 1 transposon mutants in orthologs
Commentpsl cluster plays a role in cell-cell and/or cell-surface interaction in biofilm formation.

Cross-References

RefSeq NP_250935
GI 15597441
Affymetrix PA2245_at
GenBank AAG05633.1
protein_id(GenBank) gb|AAG05633.1|AE004650_4|gnl|PseudoCAP|PA2245
TIGR NTL03PA02245
UniProtKB Acc Q9I1M4
UniProtKB ID Q9I1M4_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 0.70
Kyte-Doolittle Hydrophobicity Value 0.569
Molecular Weight (kDa) 10.6
Isoelectric Point (pI) 7.80

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Pathogenic
Found only in pathogenic strains
Hits to this gene were found in one genus

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003242 (4 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA2245
Search term: pslO

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295