Pseudomonas aeruginosa PAO1, PA3604 (erdR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3604
Name
erdR
Synonym: ErdR
Replicon chromosome
Genomic location 4038388 - 4039041 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252294.1
GI 15598800
Affymetrix PA3604_at
DNASU PaCD00007578
Entrez 880150
GenBank AAG06992.1
INSDC AAG06992.1
NCBI Locus Tag PA3604
protein_id(GenBank) gb|AAG06992.1|AE004780_11|gnl|PseudoCAP|PA3604
TIGR NTL03PA03604
UniParc UPI00000C5A89
UniProtKB Acc Q9HY22
UniProtKB ID Q9HY22_PSEAE
UniRef100 UniRef100_W0YW65
UniRef50 UniRef50_Q6LLZ9
UniRef90 UniRef90_A0A024HC99

Product

Feature Type CDS
Coding Frame 1
Product Name
response regulator ErdR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -7.07
Kyte-Doolittle Hydrophobicity Value 0.091
Molecular Weight (kDa) 23.5
Isoelectric Point (pI) 4.75

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 535 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002070 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3604
Search term: erdR

Human Homologs

References

The agmR gene, an environmentally responsive gene, complements defective glpR, which encodes the putative activator for glycerol metabolism in Pseudomonas aeruginosa.
Schweizer HP
J Bacteriol 1991 Nov;173(21):6798-806
PubMed ID: 1938886
A complex regulatory network controls aerobic ethanol oxidation in Pseudomonas aeruginosa: indication of four levels of sensor kinases and response regulators.
Mern DS, Ha SW, Khodaverdi V, Gliese N, Görisch H
Microbiology (Reading) 2010 May;156(Pt 5):1505-1516
PubMed ID: 20093290