Pseudomonas aeruginosa PAO1, PA3658 (glnD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3658
Name
glnD
Synonym: nfrX
Replicon chromosome
Genomic location 4096124 - 4098826 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_252348.1
GI 15598854
Affymetrix PA3658_glnD_at
Entrez 880565
GenBank AAG07046.1
INSDC AAG07046.1
NCBI Locus Tag PA3658
protein_id(GenBank) gb|AAG07046.1|AE004785_10|gnl|PseudoCAP|PA3658
TIGR NTL03PA03658
UniParc UPI000012B72E
UniProtKB Acc Q9Z9H0
UniProtKB ID GLND_PSEAE
UniRef100 UniRef100_Q9Z9H0
UniRef50 UniRef50_Q9Z9H0
UniRef90 UniRef90_Q9Z9H0

Product

Feature Type CDS
Coding Frame 1
Product Name
protein-PII uridylyltransferase
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -23.44
Kyte-Doolittle Hydrophobicity Value -0.327
Molecular Weight (kDa) 103.4
Isoelectric Point (pI) 5.46

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 289 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG002016 (535 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3658
Search term: glnD

Human Homologs

References

The product of the nitrogen fixation regulatory gene nfrX of Azotobacter vinelandii is functionally and structurally homologous to the uridylyltransferase encoded by glnD in enteric bacteria.
Contreras A, Drummond M, Bali A, Blanco G, Garcia E, Bush G, Kennedy C, Merrick M
J Bacteriol 1991 Dec;173(24):7741-9
PubMed ID: 1683868
The genes of the glutamine synthetase adenylylation cascade are not regulated by nitrogen in Escherichia coli.
van Heeswijk WC, Rabenberg M, Westerhoff HV, Kahn D
Mol Microbiol 1993 Aug;9(3):443-57
PubMed ID: 8412694