Pseudomonas aeruginosa PAO1, PA3706 (wspC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA3706
Name
wspC
Replicon chromosome
Genomic location 4148931 - 4150199 (- strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_252395.1
GI 15598901
Affymetrix PA3706_at
Entrez 878238
GenBank AAG07093.1
INSDC AAG07093.1
NCBI Locus Tag PA3706
protein_id(GenBank) gb|AAG07093.1|AE004789_13|gnl|PseudoCAP|PA3706
TIGR NTL03PA03706
UniParc UPI00000C5ACD
UniProtKB Acc Q9HXT5
UniProtKB ID WSPC_PSEAE
UniRef100 UniRef100_Q9HXT5
UniRef50 UniRef50_Q9HXT5
UniRef90 UniRef90_Q9HXT5

Product

Feature Type CDS
Coding Frame 1
Product Name
probable protein methyltransferase
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 2.58
Kyte-Doolittle Hydrophobicity Value -0.209
Molecular Weight (kDa) 46.4
Isoelectric Point (pI) 7.99

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 413 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000403 (854 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA3706
Search term: wspC

Human Homologs

References

Autolysis and autoaggregation in Pseudomonas aeruginosa colony morphology mutants.
D'Argenio DA, Calfee MW, Rainey PB, Pesci EC
J Bacteriol 2002 Dec;184(23):6481-9
PubMed ID: 12426335
"Frizzy" aggregation genes of the gliding bacterium Myxococcus xanthus show sequence similarities to the chemotaxis genes of enteric bacteria.
McBride MJ, Weinberg RA, Zusman DR
Proc Natl Acad Sci U S A 1989 Jan;86(2):424-8
PubMed ID: 2492105
Developmental sensory transduction in Myxococcus xanthus involves methylation and demethylation of FrzCD.
McCleary WR, McBride MJ, Zusman DR
J Bacteriol 1990 Sep;172(9):4877-87
PubMed ID: 2168368