Pseudomonas aeruginosa PAO1, PA5457

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5457
Name
Replicon chromosome
Genomic location 6148319 - 6149182 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_254144.1
GI 15600650
Affymetrix PA5457_at
Entrez 883023
GenBank AAG08842.1
INSDC AAG08842.1
NCBI Locus Tag PA5457
protein_id(GenBank) gb|AAG08842.1|AE004958_12|gnl|PseudoCAP|PA5457
TIGR NTL03PA05458
UniParc UPI00000C6016
UniProtKB Acc Q9HTB3
UniProtKB ID Q9HTB3_PSEAE
UniRef100 UniRef100_Q9HTB3
UniRef50 UniRef50_Q9HTB3
UniRef90 UniRef90_Q9HTB3

Product

Feature Type CDS
Coding Frame 1
Product Name
methyltransferase
Product Name Confidence: Class 2
Synonyms putative methyltransferase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -3.43
Kyte-Doolittle Hydrophobicity Value -0.093
Molecular Weight (kDa) 31.7
Isoelectric Point (pI) 6.17

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 192 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005003 (334 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5457
Search term: methyltransferase

Human Homologs

References

Five new genes are important for common polysaccharide antigen biosynthesis in Pseudomonas aeruginosa.
Hao Y, King JD, Huszczynski S, Kocíncová D, Lam JS
mBio 2013 Jan 22;4(1):e00631-12
PubMed ID: 23341552