Pseudomonas aeruginosa PAO1, PA5559 (atpE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA5559
Name
atpE
Synonym: uncE
Synonym: papH
Replicon chromosome
Genomic location 6253235 - 6253492 (- strand)

Cross-References

RefSeq NP_254246.1
GI 15600752
Affymetrix PA5559_atpE_at
DNASU PaCD00007317
Entrez 880088
GenBank AAG08944.1
INSDC AAG08944.1
NCBI Locus Tag PA5559
protein_id(GenBank) gb|AAG08944.1|AE004967_15|gnl|PseudoCAP|PA5559
TIGR NTL03PA05560
UniParc UPI000000FE1D
UniProtKB Acc Q9HT15
UniProtKB ID ATPL_PSEAE
UniRef100 UniRef100_A6VF37
UniRef50 UniRef50_B0TQF9
UniRef90 UniRef90_A6VF37

Product

Feature Type CDS
Coding Frame 1
Product Name
atp synthase C chain
Product Name Confidence: Class 2
Synonyms dicyclohexylcarbodiimide-binding protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.02
Kyte-Doolittle Hydrophobicity Value 1.311
Molecular Weight (kDa) 8.6
Isoelectric Point (pI) 4.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 196 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG005090 (519 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA5559
Search term: atpE

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Nucleotide sequence of genes coding for dicyclohexylcarbodiimide-binding protein and the alpha subunit of proton-translocating ATPase of Escherichia coli.
Kanazawa H, Mabuchi K, Kayano T, Tamura F, Futai M
Biochem Biophys Res Commun 1981 May 15;100(1):219-25
PubMed ID: 6266400
Model of the c-subunit oligomer in the membrane domain of F-ATPases.
Groth G, Walker JE
FEBS Lett 1997 Jun 30;410(2-3):117-23
PubMed ID: 9237612