Pseudomonas aeruginosa PAO1, PA0095

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0095
Name
Synonym: vgr
Synonym: VgrG1b
Replicon chromosome
Genomic location 115299 - 117524 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 10 transposon mutants in orthologs

Cross-References

RefSeq NP_248785.1
GI 15595293
Affymetrix PA0095_at
Entrez 880726
GenBank AAG03485.1
INSDC AAG03485.1
NCBI Locus Tag PA0095
protein_id(GenBank) gb|AAG03485.1|AE004448_4|gnl|PseudoCAP|PA0095
TIGR NTL03PA00096
UniParc UPI00000C4F30
UniProtKB Acc Q9I737
UniProtKB ID Q9I737_PSEAE
UniRef100 UniRef100_Q9I737
UniRef50 UniRef50_Q9I741
UniRef90 UniRef90_Q9I737

Product

Feature Type CDS
Coding Frame 1
Product Name
vgrG1b
Product Name Confidence: Class 1
Synonyms conserved hypothetical protein
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -19.52
Kyte-Doolittle Hydrophobicity Value -0.667
Molecular Weight (kDa) 82.8
Isoelectric Point (pI) 5.25

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 154 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000090 (3427 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0095
Search term: vgrG1b

References

Rhs elements comprise three subfamilies which diverged prior to acquisition by Escherichia coli.
Wang YD, Zhao S, Hill CW
J. Bacteriol. 1998 Aug;180(16):4102-10
PubMed ID: 9696756
Type VI secretion system in Pseudomonas aeruginosa: secretion and multimerization of VgrG proteins.
Hachani A, Lossi NS, Hamilton A, Jones C, Bleves S, Albesa-Jové D, Filloux A
J. Biol. Chem. 2011 Apr;286(14):12317-27
PubMed ID: 21325275
RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.
Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.
Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712.
PubMed ID: 28673999