Pseudomonas aeruginosa PAK, PAK_04190 (phoQ)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Feature Overview
| Strain |
Pseudomonas aeruginosa PAK - Assembly GCF_000408865.1
GCF_000408865.1|latest |
| Locus Tag |
PAK_04190
|
| Name |
phoQ
|
| Replicon | chromosome |
| Genomic location | 4549818 - 4551164 (- strand) |
Cross-References
| RefSeq | WP_003082438.1 |
| GI | 489172887 |
| NCBI Locus Tag | PAK_04190 |
Product
| Feature Type | CDS |
| Coding Frame | 1 |
| Product Name |
sensor histidine kinase
|
| Synonyms | |
| Evidence for Translation | |
| Charge (pH 7) | -4.90 |
| Kyte-Doolittle Hydrophobicity Value | -0.204 |
| Molecular Weight (kDa) | 50.2 |
| Isoelectric Point (pI) | 6.09 |
Subcellular localization
| Individual Mappings | |
| Additional evidence for subcellular localization |
AlphaFold 2 Protein Structure Predictions
Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.
Orthologs/Comparative Genomics
| Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
| Pseudomonas Ortholog Group |
POG001138 (522 members) |
| Putative Inparalogs | None Found |
Interactions
| STRING database | Search for predicted protein-protein interactions using:
Search term: PAK_04190
Search term: phoQ
Search term: sensor histidine kinase
|
Human Homologs
References
|
PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients.
Miller AK, Brannon MK, Stevens L, Johansen HK, Selgrade SE, Miller SI, Høiby N, Moskowitz SM
Antimicrob Agents Chemother 2011 Dec;55(12):5761-9
PubMed ID: 21968359
|