Pseudomonas aeruginosa PAK, PAK_04191 (phoP)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Pseudomonas aeruginosa PAK - Assembly GCF_000408865.1
GCF_000408865.1|latest
Locus Tag
PAK_04191
Name
phoP
Replicon chromosome
Genomic location 4551161 - 4551838 (- strand)

Cross-References

RefSeq WP_003082436.1
GI 489172885
NCBI Locus Tag PAK_04191

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator
Synonyms
Evidence for Translation
Charge (pH 7) -7.37
Kyte-Doolittle Hydrophobicity Value -0.267
Molecular Weight (kDa) 25.7
Isoelectric Point (pI) 5.21

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001137 (524 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PAK_04191
Search term: phoP

Human Homologs

References

PhoQ mutations promote lipid A modification and polymyxin resistance of Pseudomonas aeruginosa found in colistin-treated cystic fibrosis patients.
Miller AK, Brannon MK, Stevens L, Johansen HK, Selgrade SE, Miller SI, Høiby N, Moskowitz SM
Antimicrob Agents Chemother 2011 Dec;55(12):5761-9
PubMed ID: 21968359