Pseudomonas aeruginosa PAO1, PA0226

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0226
Name
Replicon chromosome
Genomic location 255481 - 256332 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248917.1
GI 15595423
Affymetrix PA0226_at
DNASU PaCD00006101
Entrez 878086
GenBank AAG03615.1
INSDC AAG03615.1
NCBI Locus Tag PA0226
protein_id(GenBank) gb|AAG03615.1|AE004460_8|gnl|PseudoCAP|PA0226
TIGR NTL03PA00227
UniParc UPI00000C4FA9
UniProtKB Acc Q9I6R2
UniProtKB ID Q9I6R2_PSEAE
UniRef100 UniRef100_W0YME6
UniRef50 UniRef50_A0A0B9A5L7
UniRef90 UniRef90_W0YME6

Product

Feature Type CDS
Coding Frame 1
Product Name
probable CoA transferase, subunit A
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Charge (pH 7) -3.99
Kyte-Doolittle Hydrophobicity Value -0.047
Molecular Weight (kDa) 30.9
Isoelectric Point (pI) 6.24

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 119 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000225 (497 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0226

Human Homologs

References

Glutaconate CoA-transferase from Acidaminococcus fermentans: the crystal structure reveals homology with other CoA-transferases.
Jacob U, Mack M, Clausen T, Huber R, Buckel W, Messerschmidt A
Structure 1997 Mar 15;5(3):415-26
PubMed ID: 9083111