Pseudomonas aeruginosa PAO1, PA0292 (aguA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0292
Name
aguA
Replicon chromosome
Genomic location 328801 - 329907 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_248983.1
GI 15595489
Affymetrix PA0292_at
Entrez 879730
GenBank AAG03681.1
INSDC AAG03681.1
NCBI Locus Tag PA0292
protein_id(GenBank) gb|AAG03681.1|AE004467_3|gnl|PseudoCAP|PA0292
TIGR NTL03PA00293
UniParc UPI00000C4FE7
UniProtKB Acc Q9I6J9
UniProtKB ID AGUA_PSEAE
UniRef100 UniRef100_Q9I6J9
UniRef50 UniRef50_Q8GWW7
UniRef90 UniRef90_Q9I6J9

Product

Feature Type CDS
Coding Frame 1
Product Name
agmatine deiminase
Product Name Confidence: Class 1
Synonyms agmatine iminohydrolase
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -18.27
Kyte-Doolittle Hydrophobicity Value -0.495
Molecular Weight (kDa) 41.2
Isoelectric Point (pI) 4.59

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 220 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000289 (536 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0292
Search term: aguA

Human Homologs

References

Molecular characterization and regulation of the aguBA operon, responsible for agmatine utilization in Pseudomonas aeruginosa PAO1.
Nakada Y, Jiang Y, Nishijyo T, Itoh Y, Lu CD
J Bacteriol 2001 Nov;183(22):6517-24
PubMed ID: 11673419