Pseudomonas aeruginosa PAO1, PA0314

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0314
Name
Synonym: fliY
Replicon chromosome
Genomic location 353691 - 354461 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs
CommentReference gives strong physiological evidence, BLAST: E-values (<10^-45).

Cross-References

RefSeq NP_249005.1
GI 15595511
Affymetrix PA0314_at
Entrez 878270
GenBank AAG03703.1
INSDC AAG03703.1
NCBI Locus Tag PA0314
protein_id(GenBank) gb|AAG03703.1|AE004469_8|gnl|PseudoCAP|PA0314
TIGR NTL03PA00315
UniParc UPI00000C4FFD
UniProtKB Acc Q9I6H7
UniProtKB ID Q9I6H7_PSEAE
UniRef100 UniRef100_W0YKA9
UniRef50 UniRef50_A1W7Q8
UniRef90 UniRef90_A1W7Q8

Product

Feature Type CDS
Coding Frame 1
Product Name
L-cysteine transporter of ABC system FliY
Product Name Confidence: Class 3
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 4.48
Kyte-Doolittle Hydrophobicity Value -0.152
Molecular Weight (kDa) 28.0
Isoelectric Point (pI) 9.65

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 466 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000311 (491 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0314

Human Homologs

References

Analysis of global responses by protein and peptide fingerprinting of proteins isolated by two-dimensional gel electrophoresis. Application to the sulfate-starvation response of Escherichia coli.
Quadroni M, Staudenmann W, Kertesz M, James P
Eur J Biochem 1996 Aug 1;239(3):773-81
PubMed ID: 8774726
Amino acid transport in Pseudomonas aeruginosa.
Kay WW, Gronlund AF
J Bacteriol 1969 Jan;97(1):273-81
PubMed ID: 4974392