Pseudomonas aeruginosa PAO1, PA0448 (gcdR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0448
Name
gcdR
Replicon chromosome
Genomic location 504121 - 505029 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249139.1
GI 15595645
Affymetrix PA0448_at
Entrez 881014
GenBank AAG03837.1
INSDC AAG03837.1
NCBI Locus Tag PA0448
protein_id(GenBank) gb|AAG03837.1|AE004482_4|gnl|PseudoCAP|PA0448
TIGR NTL03PA00449
UniParc UPI00000C505E
UniProtKB Acc Q9I670
UniProtKB ID Q9I670_PSEAE
UniRef100 UniRef100_A0A081HDG5
UniRef50 UniRef50_Q4KKG5
UniRef90 UniRef90_W0YLS5

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator, GcdR
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) 1.87
Kyte-Doolittle Hydrophobicity Value -0.153
Molecular Weight (kDa) 34.0
Isoelectric Point (pI) 7.73

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 494 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000439 (1061 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0448
Search term: gcdR

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 2566
Genomic Position 504304
Position in ORF 184(909)
Reference 14617778
Type ISphoA/hah insertion site
Mutant ID UWGC: 54950
Genomic Position 504637
Position in ORF 517(909)
Reference 14617778

Transposon Insertions in Orthologs

References

Molecular characterization of lysR-lysXE, gcdR-gcdHG and amaR-amaAB operons for lysine export and catabolism: a comprehensive lysine catabolic network in Pseudomonas aeruginosa PAO1.
Madhuri Indurthi S, Chou HT, Lu CD
Microbiology (Reading, Engl.) 2016 May;162(5):876-88
PubMed ID: 26967762