Pseudomonas aeruginosa PAO1, PA0781

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0781
Name
Replicon chromosome
Genomic location 849256 - 851319 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249472.1
GI 15595978
Affymetrix PA0781_at
Entrez 882115
GenBank AAG04170.1
INSDC AAG04170.1
NCBI Locus Tag PA0781
protein_id(GenBank) gb|AAG04170.1|AE004513_2|gnl|PseudoCAP|PA0781
TIGR NTL03PA00782
UniParc UPI00000C514B
UniProtKB Acc Q9I5F7
UniProtKB ID Q9I5F7_PSEAE
UniRef100 UniRef100_Q9I5F7
UniRef50 UniRef50_Q2T7X2
UniRef90 UniRef90_Q9I5F7

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Detected by MALDI-TOF/TOF (PMID:19333994).
Charge (pH 7) -28.89
Kyte-Doolittle Hydrophobicity Value -0.484
Molecular Weight (kDa) 74.2
Isoelectric Point (pI) 4.72

Subcellular localization

Individual Mappings
Localization Confidence PMID
Outer Membrane Class 3
Outer Membrane Class 2
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 280 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000755 (453 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0781

Human Homologs

References

Divergent structure and regulatory mechanism of proline catabolic systems: characterization of the putAP proline catabolic operon of Pseudomonas aeruginosa PAO1 and its regulation by PruR, an AraC/XylS family protein.
Nakada Y, Nishijyo T, Itoh Y
J Bacteriol 2002 Oct;184(20):5633-40
PubMed ID: 12270821
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Analysis of the periplasmic proteome of Pseudomonas aeruginosa, a metabolically versatile opportunistic pathogen.
Imperi F, Ciccosanti F, Perdomo AB, Tiburzi F, Mancone C, Alonzi T, Ascenzi P, Piacentini M, Visca P, Fimia GM
Proteomics 2009 Apr;9(7):1901-15
PubMed ID: 19333994