Pseudomonas aeruginosa PAO1, PA0893 (argR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0893
Name
argR
Replicon chromosome
Genomic location 976410 - 977399 (+ strand)
Transposon Mutants 6 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249584.1
GI 15596090
Affymetrix PA0893_argR_at
DNASU PaCD00006411
Entrez 879434
GenBank AAG04282.1
INSDC AAG04282.1
NCBI Locus Tag PA0893
protein_id(GenBank) gb|AAG04282.1|AE004523_10|gnl|PseudoCAP|PA0893
TIGR NTL03PA00894
UniParc UPI00000C51AB
UniProtKB Acc G3XCU2
UniProtKB ID G3XCU2_PSEAE
UniRef100 UniRef100_W0YLE4
UniRef50 UniRef50_Q885K1
UniRef90 UniRef90_A6VA80

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator ArgR
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) 3.81
Kyte-Doolittle Hydrophobicity Value -0.219
Molecular Weight (kDa) 36.9
Isoelectric Point (pI) 8.34

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Cytoplasmic Class 1
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 419 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000860 (512 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0893
Search term: argR

Human Homologs

References

Purification and characterization of an arginine regulatory protein, ArgR, from Pseudomonas aeruginosa and its interactions with the control regions for the car, argF, and aru operons.
Park SM, Lu CD, Abdelal AT
J Bacteriol 1997 Sep;179(17):5309-17
PubMed ID: 9286981