Pseudomonas aeruginosa PAO1, PA0897 (aruG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA0897
Name
aruG
Synonym: aruAII
Replicon chromosome
Genomic location 980357 - 981379 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249588.1
GI 15596094
Affymetrix PA0897_aruG_at
Entrez 883082
GenBank AAG04286.1
INSDC AAG04286.1
NCBI Locus Tag PA0897
protein_id(GenBank) gb|AAG04286.1|AE004524_3|gnl|PseudoCAP|PA0897
TIGR NTL03PA00898
UniParc UPI00001261B2
UniProtKB Acc P80358
UniProtKB ID ASTG_PSEAE
UniRef100 UniRef100_P80358
UniRef50 UniRef50_P80358
UniRef90 UniRef90_P80358

Product

Feature Type CDS
Coding Frame 1
Product Name
subunit II of arginine N2-succinyltransferase = ornithine N2-succinyltransferase
Product Name Confidence: Class 1
Synonyms arginine/ornithine succinyltransferase AII subunit
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -2.16
Kyte-Doolittle Hydrophobicity Value -0.120
Molecular Weight (kDa) 37.2
Isoelectric Point (pI) 6.52

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 75 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000864 (513 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0897
Search term: aruG

Human Homologs

References

Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa.
Itoh Y
J Bacteriol 1997 Dec;179(23):7280-90
PubMed ID: 9393691
N-Succinylated intermediates in an arginine catabolic pathway of Pseudomonas aeruginosa.
Jann A, Stalon V, Wauven CV, Leisinger T, Haas D
Proc Natl Acad Sci U S A 1986 Jul;83(13):4937-41
PubMed ID: 16593724