Pseudomonas aeruginosa PAO1, PA0901 (aruE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0901
Name
aruE
Synonym: astE
Replicon chromosome
Genomic location 984549 - 985547 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249592.1
GI 15596098
Affymetrix PA0901_aruE_at
Entrez 878165
GenBank AAG04290.1
INSDC AAG04290.1
NCBI Locus Tag PA0901
protein_id(GenBank) gb|AAG04290.1|AE004524_7|gnl|PseudoCAP|PA0901
TIGR NTL03PA00902
UniParc UPI00001261B1
UniProtKB Acc O50177
UniProtKB ID ASTE_PSEAE
UniRef100 UniRef100_B7UY33
UniRef50 UniRef50_B7UY33
UniRef90 UniRef90_B7UY33

Product

Feature Type CDS
Coding Frame 1
Product Name
N-Succinylglutamate desuccinylase
Product Name Confidence: Class 1
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.57
Kyte-Doolittle Hydrophobicity Value -0.266
Molecular Weight (kDa) 36.9
Isoelectric Point (pI) 6.03

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 48 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000868 (552 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0901
Search term: aruE

References

Cloning and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase pathway in Pseudomonas aeruginosa.
Itoh Y
J. Bacteriol. 1997 Dec;179(23):7280-90
PubMed ID: 9393691
N-Succinylated intermediates in an arginine catabolic pathway of Pseudomonas aeruginosa.
Jann A, Stalon V, Wauven CV, Leisinger T, Haas D
Proc. Natl. Acad. Sci. U.S.A. 1986 Jul;83(13):4937-41
PubMed ID: 16593724