Pseudomonas aeruginosa PAO1, PA0906 (alpR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA0906
Name
alpR
Replicon chromosome
Genomic location 991830 - 992543 (- strand)

Cross-References

RefSeq NP_249597.1
GI 15596103
Affymetrix PA0906_at
DNASU PaCD00006417
Entrez 878520
GenBank AAG04295.1
INSDC AAG04295.1
NCBI Locus Tag PA0906
protein_id(GenBank) gb|AAG04295.1|AE004525_3|gnl|PseudoCAP|PA0906
TIGR NTL03PA00907
UniParc UPI00000C51AD
UniProtKB Acc Q9I551
UniProtKB ID Q9I551_PSEAE
UniRef100 UniRef100_W0YPB1
UniRef50 UniRef50_A6VA68
UniRef90 UniRef90_A6VA68

Product

Feature Type CDS
Coding Frame 1
Product Name
lysis phenotype repressor, AlpR
Product Name Confidence: Class 1
CommentEssential transcription regulator that represses the alp lysis genes
Evidence for Translation
Charge (pH 7) -2.86
Kyte-Doolittle Hydrophobicity Value -0.388
Molecular Weight (kDa) 25.9
Isoelectric Point (pI) 6.04

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 97 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000594 (1300 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA0906
Search term: alpR

References

A self-lysis pathway that enhances the virulence of a pathogenic bacterium.
McFarland KA, Dolben EL, LeRoux M, Kambara TK, Ramsey KM, Kirkpatrick RL, Mougous JD, Hogan DA, Dove SL
Proc. Natl. Acad. Sci. U.S.A. 2015 Jul;112(27):8433-8
PubMed ID: 26100878