Pseudomonas aeruginosa PAO1, PA0919

Cytoplasmic Membrane
Outer Membrane
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
Replicon chromosome
Genomic location 1002681 - 1003964 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs


RefSeq NP_249610.1
GI 15596116
Affymetrix PA0919_at
Entrez 877608
GenBank AAG04308.1
INSDC AAG04308.1
NCBI Locus Tag PA0919
protein_id(GenBank) gb|AAG04308.1|AE004526_3|gnl|PseudoCAP|PA0919
UniParc UPI00000C51BA
UniProtKB Acc Q9I538
UniRef100 UniRef100_W0YMS7
UniRef50 UniRef50_G8QC72
UniRef90 UniRef90_Q02I79


Feature Type CDS
Coding Frame 1
Product Name
alanyl-phosphatidylglycerol hydrolase
Product Name Confidence: Class 1
Synonyms hypothetical protein
Evidence for Translation
Detected using LC-MS/MS (46.65 kDa, PMID:21751344)
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.46
Kyte-Doolittle Hydrophobicity Value -0.305
Molecular Weight (kDa) 46.7
Isoelectric Point (pI) 5.00

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Outer Membrane Vesicle Class 1
Additional evidence for subcellular localization

Pathogen Association Analysis

Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 34 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000885 (528 members)
Putative Inparalogs None Found


STRING database Search for predicted protein-protein interactions using:
Search term: PA0919


Isolation and characterization of a new chromosomal virulence gene of Agrobacterium tumefaciens.
Wirawan IG, Kang HW, Kojima M
J. Bacteriol. 1993 May;175(10):3208-12
PubMed ID: 8491736
The octopine-type Ti plasmid pTiA6 of Agrobacterium tumefaciens contains a gene homologous to the chromosomal virulence gene acvB.
Kalogeraki VS, Winans SC
J. Bacteriol. 1995 Feb;177(4):892-7
PubMed ID: 7860597
Proteomic analysis of outer membrane vesicles derived from Pseudomonas aeruginosa.
Choi DS, Kim DK, Choi SJ, Lee J, Choi JP, Rho S, Park SH, Kim YK, Hwang D, Gho YS
Proteomics 2011 Aug;11(16):3424-9
PubMed ID: 21751344
Identification and characterization of a periplasmic aminoacyl-phosphatidylglycerol hydrolase responsible for Pseudomonas aeruginosa lipid homeostasis.
Arendt W, Groenewold MK, Hebecker S, Dickschat JS, Moser J
J. Biol. Chem. 2013 Aug;288(34):24717-30
PubMed ID: 23792962