Pseudomonas aeruginosa PAO1, PA1027 (amaB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1027
Name
amaB
Synonym: pcd
Replicon chromosome
Genomic location 1113129 - 1114718 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249718.1
GI 15596224
Affymetrix PA1027_at
Entrez 878608
GenBank AAG04416.1
INSDC AAG04416.1
NCBI Locus Tag PA1027
protein_id(GenBank) gb|AAG04416.1|AE004535_3|gnl|PseudoCAP|PA1027
TIGR NTL03PA01028
UniParc UPI00000C520F
UniProtKB Acc Q9I4U7
UniProtKB ID Q9I4U7_PSEAE
UniRef100 UniRef100_Q9I4U7
UniRef50 UniRef50_Q9DBF1
UniRef90 UniRef90_W0WL03

Product

Feature Type CDS
Coding Frame 1
Product Name
delta1-Piperideine-6-carboxylate dehydrogenase
Product Name Confidence: Class 2
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -1.02
Kyte-Doolittle Hydrophobicity Value -0.203
Molecular Weight (kDa) 57.3
Isoelectric Point (pI) 6.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 596 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000989 (526 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1027
Search term: amaB

Human Homologs

Ensembl 86, assembly GRCh38.p7
aldehyde dehydrogenase 7 family member A1 [Source:HGNC Symbol;Acc:HGNC:877]
E-value: 2.0e-126
Percent Identity: 50.0

Transposon Insertions in PAO1

Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Mutant ID UBC: PAO1_lux_43_C5
Genomic Position 1114358
Position in ORF 1230(1590)
Reference 15805499
Type ISphoA/hah insertion site
Mutant ID UWGC: 55037
Genomic Position 1113786
Position in ORF 658(1590)
Reference 14617778
Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Mutant ID UBC: PAO1_lux_97_C12
Genomic Position 1114358
Position in ORF 1230(1590)
Reference 15805499
Type ISphoA/hah insertion site
Mutant ID UWGC: 39046
Genomic Position 1113528
Position in ORF 400(1590)
Reference 14617778

Transposon Insertions in Orthologs

Type MAR2xT7 transposon (wild type background) insertion site
Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag PA14_51050
Mutant ID PA14NR: 34514
Genomic Position 4535612
Position in ORF 400(1590)
Reference 16477005

References

Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440.
Revelles O(1), Espinosa-Urgel M, Fuhrer T, Sauer U, Ramos JL.
J Bacteriol. 2005 Nov;187(21):7500-10.
PubMed ID: 16237033