Pseudomonas aeruginosa PAO1, PA1028 (amaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1028
Name
amaA
Synonym: amaB
Replicon chromosome
Genomic location 1114774 - 1116060 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1

Cross-References

RefSeq NP_249719.1
GI 15596225
Affymetrix PA1028_at
Entrez 880062
GenBank AAG04417.1
INSDC AAG04417.1
NCBI Locus Tag PA1028
protein_id(GenBank) gb|AAG04417.1|AE004535_4|gnl|PseudoCAP|PA1028
TIGR NTL03PA01029
UniParc UPI00000C5210
UniProtKB Acc Q9I4U6
UniProtKB ID Q9I4U6_PSEAE
UniRef100 UniRef100_K1CS31
UniRef50 UniRef50_D7I2F2
UniRef90 UniRef90_A0A0C6FET6

Product

Feature Type CDS
Coding Frame 1
Product Name
L-Pipecolate oxidase
Product Name Confidence: Class 2
Evidence for Translation
Charge (pH 7) 8.61
Kyte-Doolittle Hydrophobicity Value -0.061
Molecular Weight (kDa) 46.2
Isoelectric Point (pI) 8.62

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 282 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000990 (521 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1028
Search term: amaA

Transposon Insertions in PAO1

Type Confirmed ISlacZ/hah insertion site
Mutant ID UWGC: 5031
Genomic Position 1115834
Position in ORF 1061(1287)
Reference 14617778
Type ISlacZ/hah insertion site
Mutant ID UWGC: 20635
Genomic Position 1115658
Position in ORF 885(1287)
Reference 14617778
Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Mutant ID UBC: PAO1_lux_14_F4
Genomic Position 1115973
Position in ORF 1200(1287)
Reference 15805499

Transposon Insertions in Orthologs

References

Rat liver dimethylglycine dehydrogenase. Flavinylation of the enzyme in hepatocytes in primary culture and characterization of a cDNA clone.
Lang H, Polster M, Brandsch R
Eur. J. Biochem. 1991 Jun;198(3):793-9
PubMed ID: 1710985
Molecular characterization of lysR-lysXE, gcdR-gcdHG and amaR-amaAB operons for lysine export and catabolism: a comprehensive lysine catabolic network in Pseudomonas aeruginosa PAO1.
Madhuri Indurthi S, Chou HT, Lu CD
Microbiology (Reading, Engl.) 2016 May;162(5):876-88
PubMed ID: 26967762
Multiple and interconnected pathways for L-lysine catabolism in Pseudomonas putida KT2440.
Revelles O, Espinosa-Urgel M, Fuhrer T, Sauer U, Ramos JL
J. Bacteriol. 2005 Nov;187(21):7500-10
PubMed ID: 16237033