Pseudomonas aeruginosa PAO1, PA1196 (ddaR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1196
Name
ddaR
Replicon chromosome
Genomic location 1297309 - 1298709 (+ strand)
Transposon Mutants 4 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249887.1
GI 15596393
Affymetrix PA1196_at
Entrez 878419
GenBank AAG04585.1
INSDC AAG04585.1
NCBI Locus Tag PA1196
protein_id(GenBank) gb|AAG04585.1|AE004550_1|gnl|PseudoCAP|PA1196
TIGR NTL03PA01197
UniParc UPI00000C529F
UniProtKB Acc Q9I4E2
UniProtKB ID Q9I4E2_PSEAE
UniRef100 UniRef100_W0YNM0
UniRef50 UniRef50_Z2DIN3
UniRef90 UniRef90_Z2DIN3

Product

Feature Type CDS
Coding Frame 1
Product Name
transcriptional regulator DdaR
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -0.99
Kyte-Doolittle Hydrophobicity Value -0.043
Molecular Weight (kDa) 50.2
Isoelectric Point (pI) 6.68

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 452 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001154 (303 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1196
Search term: ddaR

Transposon Insertions in PAO1

Type ISphoA/hah insertion site
Mutant ID UWGC: 42052
Genomic Position 1297954
Position in ORF 646(1401)
Reference 14617778
Type ISlacZ/hah insertion site
Mutant ID UWGC: 15378
Genomic Position 1297618
Position in ORF 310(1401)
Reference 14617778
Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Mutant ID UBC: PAO1_lux_73_A6
Genomic Position 1297884
Position in ORF 576(1401)
Reference 15805499
Type mini-Tn5 lux transposon insertion site (Transcriptional fusion)
Mutant ID UBC: PAO1_lux_81_B7
Genomic Position 1297884
Position in ORF 576(1401)
Reference 15805499

Transposon Insertions in Orthologs

Type MAR2xT7 transposon (wild type background) insertion site
Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag PA14_48830
Mutant ID PA14NR: 28846
Genomic Position 4340906
Position in ORF 1268(1401)
Reference 16477005
Type MAR2xT7 transposon (wild type background) insertion site
Strain Pseudomonas aeruginosa UCBPP-PA14
Locus Tag PA14_48830
Mutant ID PA14NR: 29372
Genomic Position 4339768
Position in ORF 130(1401)
Reference 16477005

References

DdaR (PA1196) Regulates Expression of Dimethylarginine Dimethylaminohydrolase for the Metabolism of Methylarginines in Pseudomonas aeruginosa PAO1.
Lundgren BR, Bailey FJ, Moley G, Nomura CT
J. Bacteriol. 2017 Apr;199(8):
PubMed ID: 28167521