Pseudomonas aeruginosa PAO1, PA1207 (kefB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1207
Name
kefB
Synonym: kefC
Synonym: trkB
Replicon chromosome
Genomic location 1306059 - 1307900 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_249898.1
GI 15596404
Affymetrix PA1207_kefB_at
Entrez 881881
GenBank AAG04596.1
INSDC AAG04596.1
NCBI Locus Tag PA1207
protein_id(GenBank) gb|AAG04596.1|AE004550_12|gnl|PseudoCAP|PA1207
TIGR NTL03PA01208
UniParc UPI00000C52A9
UniProtKB Acc Q9I4D1
UniProtKB ID Q9I4D1_PSEAE
UniRef100 UniRef100_Q9I4D1
UniRef50 UniRef50_Q9I4D1
UniRef90 UniRef90_Q9I4D1

Product

Feature Type CDS
Coding Frame 1
Product Name
glutathione-regulated potassium-efflux system protein KefB
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -0.60
Kyte-Doolittle Hydrophobicity Value 0.496
Molecular Weight (kDa) 66.3
Isoelectric Point (pI) 6.88

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Cytoplasmic Membrane Class 2
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 493 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001164 (517 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1207
Search term: kefB

References

Evidence for multiple K+ export systems in Escherichia coli.
Bakker EP, Booth IR, Dinnbier U, Epstein W, Gajewska A
J. Bacteriol. 1987 Aug;169(8):3743-9
PubMed ID: 3301813
Activation of potassium channels during metabolite detoxification in Escherichia coli.
Ferguson GP, Munro AW, Douglas RM, McLaggan D, Booth IR
Mol. Microbiol. 1993 Sep;9(6):1297-303
PubMed ID: 7934942