Pseudomonas aeruginosa PAO1, PA1259 (lhpH)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1259
Name
lhpH
Replicon chromosome
Genomic location 1366538 - 1368280 (- strand)
Transposon Mutants 2 transposon mutants in PAO1

Cross-References

RefSeq NP_249950.1
GI 15596456
Affymetrix PA1259_at
Entrez 881330
GenBank AAG04648.1
INSDC AAG04648.1
NCBI Locus Tag PA1259
protein_id(GenBank) gb|AAG04648.1|AE004555_8|gnl|PseudoCAP|PA1259
TIGR NTL03PA01260
UniParc UPI00000C52D5
UniProtKB Acc Q9I485
UniProtKB ID Q9I485_PSEAE
UniRef100 UniRef100_Q9I485
UniRef50 UniRef50_Q9I485
UniRef90 UniRef90_Q9I485

Product

Feature Type CDS
Coding Frame 1
Product Name
LhpH
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -4.31
Kyte-Doolittle Hydrophobicity Value 0.043
Molecular Weight (kDa) 61.8
Isoelectric Point (pI) 6.55

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 90 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001210 (347 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1259
Search term: lhpH
Search term: LhpH

Transposon Insertions in PAO1

Type ISphoA/hah insertion site
Mutant ID UWGC: 43169
Genomic Position 1368183
Position in ORF 1646(1743)
Reference 14617778
Type Confirmed ISphoA/hah insertion site
Mutant ID UWGC: 39636
Genomic Position 1367399
Position in ORF 862(1743)
Reference 14617778

Transposon Insertions in Orthologs

References

Molecular characterization of LhpR in control of hydroxyproline catabolism and transport in Pseudomonas aeruginosa PAO1.
Li G, Lu CD
Microbiology (Reading, Engl.) 2016 Jul;162(7):1232-42
PubMed ID: 27145750