Pseudomonas aeruginosa PAO1, PA1267 (lhpB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1267
Name
lhpB
Replicon chromosome
Genomic location 1376327 - 1377442 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_249958.1
GI 15596464
Affymetrix PA1267_at
Entrez 881399
GenBank AAG04656.1
INSDC AAG04656.1
NCBI Locus Tag PA1267
protein_id(GenBank) gb|AAG04656.1|AE004556_6|gnl|PseudoCAP|PA1267
TIGR NTL03PA01268
UniParc UPI00000C52DD
UniProtKB Acc Q9I477
UniProtKB ID Q9I477_PSEAE
UniRef100 UniRef100_Q9I477
UniRef50 UniRef50_A0A022NPY8
UniRef90 UniRef90_A0A022NPY8

Product

Feature Type CDS
Coding Frame 1
Product Name
D-hydroxyproline dehydrogenase beta-subunit, LphB
Product Name Confidence: Class 1
Evidence for Translation
Charge (pH 7) -1.22
Kyte-Doolittle Hydrophobicity Value 0.016
Molecular Weight (kDa) 39.1
Isoelectric Point (pI) 6.72

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Membrane Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 367 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001217 (411 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1267
Search term: lhpB

References

Molecular characterization of LhpR in control of hydroxyproline catabolism and transport in Pseudomonas aeruginosa PAO1.
Li G, Lu CD
Microbiology (Reading, Engl.) 2016 Jul;162(7):1232-42
PubMed ID: 27145750
Identification and characterization of D-hydroxyproline dehydrogenase and Delta1-pyrroline-4-hydroxy-2-carboxylate deaminase involved in novel L-hydroxyproline metabolism of bacteria: metabolic convergent evolution.
Watanabe S, Morimoto D, Fukumori F, Shinomiya H, Nishiwaki H, Kawano-Kawada M, Sasai Y, Tozawa Y, Watanabe Y
J. Biol. Chem. 2012 Sep;287(39):32674-88
PubMed ID: 22833679