Pseudomonas aeruginosa PAO1, PA1559

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1559
Name
Replicon chromosome
Genomic location 1697188 - 1697919 (+ strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250250
GI 15596756
Affymetrix PA1559_at
DNASU PaCD00006712
Entrez 883111
GenBank AAG04948.1
NCBI Locus Tag PA1559
protein_id(GenBank) gb|AAG04948.1|AE004584_4|gnl|PseudoCAP|PA1559
TIGR NTL03PA01560
UniProtKB Acc Q9I3F8
UniProtKB ID Q9I3F8_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
hypothetical protein
Product Name Confidence: Class 4
Synonyms
Evidence for Translation
Charge (pH 7) 1.02
Kyte-Doolittle Hydrophobicity Value -0.074
Molecular Weight (kDa) 26551.0
Isoelectric Point (pI) 7.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 62 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003804 (305 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1559

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
Pseudomonas aeruginosa high-level resistance to polymyxins and other antimicrobial peptides requires cprA, a gene that is disrupted in the PAO1 strain.
Gutu AD, Rodgers NS, Park J, Moskowitz SM
Antimicrob Agents Chemother 2015 Sep;59(9):5377-87
PubMed ID: 26100714