Pseudomonas aeruginosa PAO1, PA1658 (hsiC2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1658
Name
hsiC2
Replicon chromosome
Genomic location 1805753 - 1807228 (+ strand)
Transposon Mutants 3 transposon mutants in PAO1
Transposon Mutants in orthologs 5 transposon mutants in orthologs

Cross-References

RefSeq NP_250349.1
GI 15596855
Affymetrix PA1658_at
Entrez 879592
GenBank AAG05047.1
INSDC AAG05047.1
NCBI Locus Tag PA1658
protein_id(GenBank) gb|AAG05047.1|AE004593_9|gnl|PseudoCAP|PA1658
TIGR NTL03PA01659
UniParc UPI00000C5430
UniProtKB Acc Q9I367
UniProtKB ID Q9I367_PSEAE
UniRef100 UniRef100_W0YRR8
UniRef50 UniRef50_G8Q745
UniRef90 UniRef90_G8Q745

Product

Feature Type CDS
Coding Frame 1
Product Name
HsiC2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -13.39
Kyte-Doolittle Hydrophobicity Value -0.432
Molecular Weight (kDa) 55.6
Isoelectric Point (pI) 5.10

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database PseudoCAP
Category Hcp secretion island-2 encoded type VI secretion system (H2-T6SS)
Evidence ECO:0000317
genomic context evidence used in manual assertion
Host Organism Homo sapiens
Notes H2-T6SS rendered inactive via clpV2 deletion.
Reference 22665491

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 111 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000083 (1225 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1658
Search term: hsiC2
Search term: HsiC2

Human Homologs

References

No references are associated with this feature.