Pseudomonas aeruginosa PAO1, PA1668 (dotU2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1668
Name
dotU2
Replicon chromosome
Genomic location 1818189 - 1819058 (+ strand)
Transposon Mutants 1 transposon mutants in PAO1
Transposon Mutants in orthologs 2 transposon mutants in orthologs

Cross-References

RefSeq NP_250359.1
GI 15596865
Affymetrix PA1668_at
DNASU PaCD00006755
Entrez 882100
GenBank AAG05057.1
INSDC AAG05057.1
NCBI Locus Tag PA1668
protein_id(GenBank) gb|AAG05057.1|AE004594_9|gnl|PseudoCAP|PA1668
TIGR NTL03PA01669
UniParc UPI00000C543A
UniProtKB Acc Q9I357
UniProtKB ID Q9I357_PSEAE
UniRef100 UniRef100_W0YQ12
UniRef50 UniRef50_G8Q736
UniRef90 UniRef90_W0YQ12

Product

Feature Type CDS
Coding Frame 1
Product Name
DotU2
Product Name Confidence: Class 2
Synonyms
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -5.64
Kyte-Doolittle Hydrophobicity Value -0.102
Molecular Weight (kDa) 32.7
Isoelectric Point (pI) 5.43

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 101 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG000077 (829 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1668
Search term: dotU2
Search term: DotU2

Human Homologs

References

Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295