Pseudomonas aeruginosa PAO1, PA1700 (pcr2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1700
Name
pcr2
Synonym: pcr2
Replicon chromosome
Genomic location 1848339 - 1848710 (+ strand)

Cross-References

RefSeq NP_250391.1
GI 15596897
Affymetrix PA1700_at
Entrez 878424
GenBank AAG05089.1
INSDC AAG05089.1
NCBI Locus Tag PA1700
protein_id(GenBank) gb|AAG05089.1|AE004597_3|gnl|PseudoCAP|PA1700
TIGR NTL03PA01701
UniParc UPI00000C5451
UniProtKB Acc Q9I329
UniProtKB ID Q9I329_PSEAE
UniRef100 UniRef100_Q9I329
UniRef50 UniRef50_O30533
UniRef90 UniRef90_O30533

Product

Feature Type CDS
Coding Frame 1
Product Name
Pcr2
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) 0.80
Kyte-Doolittle Hydrophobicity Value 0.135
Molecular Weight (kDa) 13.7
Isoelectric Point (pI) 7.41

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Extracellular Class 1
Western blot evidence
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0083
Category T3SS
Evidence
Host Organism
Notes
Reference 11372029

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 5 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003689 (309 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1700
Search term: pcr2
Search term: Pcr2

Human Homologs

References

The lcrE gene is part of an operon in the lcr region of Yersinia enterocolitica O:3.
Viitanen AM, Toivanen P, Skurnik M
J Bacteriol 1990 Jun;172(6):3152-62
PubMed ID: 2160939
Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon.
Yahr TL, Mende-Mueller LM, Friese MB, Frank DW
J Bacteriol 1997 Nov;179(22):7165-8
PubMed ID: 9371466
Regulatory role of PopN and its interacting partners in type III secretion of Pseudomonas aeruginosa.
Yang H, Shan Z, Kim J, Wu W, Lian W, Zeng L, Xing L, Jin S
J Bacteriol 2007 Apr;189(7):2599-609
PubMed ID: 17237176