Pseudomonas aeruginosa PAO1, PA1705 (pcrG)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1705
Name
pcrG
Replicon chromosome
Genomic location 1851991 - 1852278 (+ strand)

Cross-References

RefSeq NP_250396
GI 15596902
Affymetrix PA1705_pcrG_i_at
DNASU PaCD00006772
Entrez 879383
GenBank AAG05094.1
NCBI Locus Tag PA1705
protein_id(GenBank) gb|AAG05094.1|AE004597_8|gnl|PseudoCAP|PA1705
TIGR NTL03PA01706
UniProtKB Acc Q9I326
UniProtKB ID Q9I326_PSEAE

Product

Feature Type CDS
Coding Frame 1
Product Name
regulator in type III secretion
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -5.00
Kyte-Doolittle Hydrophobicity Value -0.652
Molecular Weight (kDa) 11.0
Isoelectric Point (pI) 4.49

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Virulence Evidence

Source 1
Database VFDB : VF0083
Category T3SS
Evidence
Host Organism
Notes
Reference 11372029

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 5 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003684 (309 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1705
Search term: pcrG

Human Homologs

References

Identification of type III secreted products of the Pseudomonas aeruginosa exoenzyme S regulon.
Yahr TL, Mende-Mueller LM, Friese MB, Frank DW
J Bacteriol 1997 Nov;179(22):7165-8
PubMed ID: 9371466
Control of effector export by the Pseudomonas aeruginosa type III secretion proteins PcrG and PcrV.
Lee PC, Stopford CM, Svenson AG, Rietsch A
Mol Microbiol 2010 Feb;75(4):924-41
PubMed ID: 20487288