Pseudomonas aeruginosa PAO1, PA1780 (nirD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1780
Name
nirD
Synonym: nasE
Replicon chromosome
Genomic location 1925797 - 1926123 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250471.1
GI 15596977
Affymetrix PA1780_nirD_at
DNASU PaCD00006811
Entrez 878289
GenBank AAG05169.1
INSDC AAG05169.1
NCBI Locus Tag PA1780
protein_id(GenBank) gb|AAG05169.1|AE004603_9|gnl|PseudoCAP|PA1780
TIGR NTL03PA01781
UniParc UPI00000C5493
UniProtKB Acc Q9I2W2
UniProtKB ID Q9I2W2_PSEAE
UniRef100 UniRef100_Q9I2W2
UniRef50 UniRef50_A4G2B3
UniRef90 UniRef90_Q9I2W2

Product

Feature Type CDS
Coding Frame 1
Product Name
assimilatory nitrite reductase small subunit
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -3.20
Kyte-Doolittle Hydrophobicity Value -0.051
Molecular Weight (kDa) 11.6
Isoelectric Point (pI) 5.53

Subcellular localization

Individual Mappings
Localization Confidence PMID
Unknown Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 276 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003615 (811 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1780
Search term: nirD

Human Homologs

References

The nasB operon and nasA gene are required for nitrate/nitrite assimilation in Bacillus subtilis.
Ogawa K, Akagawa E, Yamane K, Sun ZW, LaCelle M, Zuber P, Nakano MM
J Bacteriol 1995 Mar;177(5):1409-13
PubMed ID: 7868621
Gene cluster for dissimilatory nitrite reductase (nir) from Pseudomonas aeruginosa: sequencing and identification of a locus for heme d1 biosynthesis.
Kawasaki S, Arai H, Kodama T, Igarashi Y
J Bacteriol 1997 Jan;179(1):235-42
PubMed ID: 8982003