Pseudomonas aeruginosa PAO1, PA1785 (nasT)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest
Locus Tag
PA1785
Name
nasT
Synonym: nasT
Replicon chromosome
Genomic location 1933054 - 1933632 (- strand)
Transposon Mutants 2 transposon mutants in PAO1
Transposon Mutants in orthologs 1 transposon mutants in orthologs

Cross-References

RefSeq NP_250476.1
GI 15596982
Affymetrix PA1785_at
DNASU PaCD00006813
Entrez 879976
GenBank AAG05174.1
INSDC AAG05174.1
NCBI Locus Tag PA1785
protein_id(GenBank) gb|AAG05174.1|AE004604_4|gnl|PseudoCAP|PA1785
TIGR NTL03PA01786
UniParc UPI00000C5498
UniProtKB Acc Q9I2V7
UniProtKB ID Q9I2V7_PSEAE
UniRef100 UniRef100_Q9I2V7
UniRef50 UniRef50_G8Q321
UniRef90 UniRef90_Q9I2V7

Product

Feature Type CDS
Coding Frame 1
Product Name
NasT
Product Name Confidence: Class 1
Synonyms
Evidence for Translation
Charge (pH 7) -2.34
Kyte-Doolittle Hydrophobicity Value -0.157
Molecular Weight (kDa) 21.6
Isoelectric Point (pI) 5.79

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 281 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003612 (495 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1785
Search term: nasT
Search term: NasT

Human Homologs

References

nasST, two genes involved in the induction of the assimilatory nitrite-nitrate reductase operon (nasAB) of Azotobacter vinelandii.
Gutierrez JC, Ramos F, Ortner L, Tortolero M
Mol Microbiol 1995 Nov;18(3):579-91
PubMed ID: 8748040
Transcriptional regulation of nitrate assimilation in Pseudomonas aeruginosa occurs via transcriptional antitermination within the nirBD-PA1779-cobA operon.
Romeo A, Sonnleitner E, Sorger-Domenigg T, Nakano M, Eisenhaber B, Bläsi U
Microbiology (Reading) 2012 Jun;158(Pt 6):1543-1552
PubMed ID: 22493305