Pseudomonas aeruginosa PAO1, PA1816 (dnaQ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Feature Overview

Strain Pseudomonas aeruginosa PAO1 (Reference)
Locus Tag
PA1816
Name
dnaQ
Synonym: mutD
Replicon chromosome
Genomic location 1973470 - 1974210 (+ strand)

Cross-References

RefSeq NP_250507.1
GI 15597013
Affymetrix PA1816_dnaQ_at
DNASU PaCD00006821
Entrez 877654
GenBank AAG05205.1
INSDC AAG05205.1
NCBI Locus Tag PA1816
protein_id(GenBank) gb|AAG05205.1|AE004608_4|gnl|PseudoCAP|PA1816
TIGR NTL03PA01817
UniParc UPI00000C4ED5
UniProtKB Acc G3XD54
UniProtKB ID G3XD54_PSEAE
UniRef100 UniRef100_W0YQY9
UniRef50 UniRef50_Q9CPE0
UniRef90 UniRef90_A6V704

Product

Feature Type CDS
Coding Frame 1
Product Name
DNA polymerase III, epsilon chain
Product Name Confidence: Class 2
Evidence for Translation
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
Charge (pH 7) -9.16
Kyte-Doolittle Hydrophobicity Value -0.205
Molecular Weight (kDa) 26.8
Isoelectric Point (pI) 5.02

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 481 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG003582 (561 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA1816
Search term: dnaQ

References

Structure and function of dnaQ and mutD mutators of Escherichia coli.
Takano K, Nakabeppu Y, Maki H, Horiuchi T, Sekiguchi M
Mol. Gen. Genet. 1986 Oct;205(1):9-13
PubMed ID: 3540531
Mutational analysis of the 3'-->5' proofreading exonuclease of Escherichia coli DNA polymerase III.
Taft-Benz SA, Schaaper RM
Nucleic Acids Res. 1998 Sep;26(17):4005-11
PubMed ID: 9705512
The C-terminal domain of dnaQ contains the polymerase binding site.
Taft-Benz SA, Schaaper RM
J. Bacteriol. 1999 May;181(9):2963-5
PubMed ID: 10217794